The cerebral aqueduct (also known as the aqueduct of Sylvius) is a narrow channel that connects the third and fourth ventricles of the brain, allowing cerebrospinal fluid (CSF) to flow between them.
In this post, we’ll break down the structure, location, and importance of the cerebral aqueduct with a clear, labeled diagram.
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This diagram shows the cerebral aqueduct in its anatomical context within the midbrain, connecting the third and fourth ventricles. |
Where Is the Cerebral Aqueduct Located?
- Situated in the midbrain (mesencephalon)
- Runs posterior to the midbrain tegmentum and anterior to the tectum
- Lies within the periaqueductal gray matter, which plays a role in pain modulation
Function of the Cerebral Aqueduct
- Acts as a channel for cerebrospinal fluid (CSF)
- Maintains normal CSF circulation between:
-Fourth ventricle (below)
Clinical Relevance
Blockage of the cerebral aqueduct can lead to:
- Non-communicating (obstructive) hydrocephalus
- Increased intracranial pressure
- Symptoms such as headache, nausea, vomiting, and papilledema
Causes of aqueductal stenosis include:
- Congenital narrowing
- Tumors compressing the midbrain
- Infections or hemorrhage
How to Remember It Easily
Mnemonic: “3 → 4 through the Aqueduct’s Door”
(A simple phrase to remember the CSF pathway from the third to fourth ventricles)
Suggested Study Tip
Always learn ventricular anatomy in relation to brain structures – draw connections between ventricles, CSF flow, and surrounding gray/white matter to retain long-term understanding.