Cardiac Muscle Histology & Quiz


 Cardiac muscle is a specialized involuntary striated muscle found only in the heart. Understanding its unique histological structure is crucial for medical students and healthcare professionals, especially when distinguishing it from skeletal and smooth muscle under the microscope. This post breaks down the anatomy, location, and clinical relevance of cardiac muscle in an easy-to-understand way with clear visuals.


Q: Where is cardiac muscle found?
A: In the myocardium layer of the heart wall.


2. Q: What type of muscle is cardiac muscle – voluntary or involuntary?
A: Involuntary.


3. Q: What is the shape of a cardiac muscle cell?
A: Branched and cylindrical.


4. Q: How many nuclei do cardiac muscle cells typically have?
A: Usually one centrally located nucleus; occasionally two.


5. Q: What structures connect adjacent cardiac muscle cells?
A: Intercalated discs.


6. Q: What is the function of intercalated discs?
A: They allow mechanical and electrical coupling between cells through desmosomes and gap junctions.


7. Q: Do cardiac muscle cells show striations?
A: Yes, similar to skeletal muscle due to actin and myosin filaments.


8. Q: What is the significance of gap junctions in cardiac muscle?
A: They permit the rapid spread of action potentials, enabling synchronized contraction.


9. Q: Which organelle is abundant in cardiac muscle cells and why?
A: Mitochondria – because cardiac muscle needs continuous energy for contraction.


10. Q: What distinguishes cardiac muscle from skeletal muscle under a microscope?
A: Cardiac muscle has branching fibers, central nuclei, and intercalated discs, whereas skeletal muscle is unbranched, multinucleated, and lacks intercalated discs.


11. Q: Name one pathological change seen in cardiac muscle after myocardial infarction.
A: Coagulative necrosis with loss of striations and infiltration of neutrophils.


12. Q: Why is cardiac muscle fatigue-resistant?
A: Due to its rich supply of mitochondria and continuous blood supply.


13. Q: Can cardiac muscle regenerate after injury?
A: Very limited capacity; most damage results in fibrosis.


14. Q: Which ion plays a key role in cardiac muscle contraction?
A: Calcium (Ca²⁺).


15. Q: What type of muscle is cardiac muscle embryologically derived from?
A: Mesoderm (specifically splanchnic mesoderm).







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